Melanocytes are skin cells that produce melanin responsible for the skin’s color. Brown spots are due to an increase in the number of melanocytes and the overproduction of melanin.
Exposure to sunlight stimulates the process of pigmentation and causes skin tanning.
In certain cases, the pigmentation process is disturbed and zones of brown spots appear.
Sun exposure, oral contraceptives, pregnancy, endocrine dysfunction and genetic predisposition have all been implicated in the etiology of melasma. Among these, exposure to ultraviolet radiation is thought to be the most important factor. It is well known that the enzyme tyrosinase plays a key role in melanogenesis as it regulates the rate-limiting step of melanogenesis.
DEPIGMENT depigmenting cream is an active complex that fades away brown spots caused by abnormal pigmentation including secescence marks, chloasma, photo-sensitization marks and hyperpigmentations caused by UV rays.
N-butyl resocinol has an inhibitory effect on both tyrosinase and tyrosinase-related protein-1 enzymes. It reduces melanin biosynthesis resulting in the reduction of hyper-pigmentation in the skin. It also blocks Melanosome transfer from Melanocytes to keratinocytes
Active herbal extract of black mulberry reduces the activity of the enzyme tyrosinase within the skin.
Vitamin E, contained in wheat germ oil, effectively tones and conditions the skin while improving the appearance of blemishes and dark skin colors.
Allantoin eases and soothes the skin while enhancing cell-regeneration. This enhances the new skin color and refines the skin texture with greater clarity.
DERMATOLOGICALLY TESTED, FRAGRANCE-FREE, HYDROQUINONE-FREE.
INSTRUCTIONS FOR USE:
To a cleansed face, apply a thin coat of the cream over the pigmented areas to be treated. Apply twice a day. During daytime, use of a sun block cream is highly recommended. Results are visible within 6-8 weeks, depending on the intensity of the marks.